Luis Royo first published his comics in magazines like 1984, Rambla, El Víbora, and Heavy Metal. He has created book covers for such prestigious publishers as Tor Books, Berkley Books, Avon, Warner Books, and Batman Books. Magazines often used Luis Royo's artwork to illustrate their covers, including US magazines Heavy Metal and National Lampoon and European magazines Cimoc, Cómic Art, Ere Comprime, and Total Metal.
Throughout his long career, Luis Royo has exhibited his work at art shows and galleries in France, Spain, Belgium, Germany, Russia, and the USA. He has also been awarded numerous prizes, including the Spectrum Silver Award (The Best in Contemporary, Fantastic Art) and The Inkpot Comic Art Award (Comi-Con International San Diego) in the USA, and the Peregrino Fantasy Prize in CTPAHHNK, in Russia, and the Fumetto Cartoomics Millenium award in Italy.